Since VOCs has actually small physiological 50 % of-lifetime, membership when you look at the blood tend to reflect exposures and this took place the brand new few hours instantly preceding blood range. But really, air profile about NHANES studies had been measured with passive individual monitors over symptoms regarding 2 or 3 days. Ergo, when the exposures changed significantly over the years bills out of hours, sky and you will bloodstream accounts throughout the mix-sectional NHANES database would be increasingly discordant. (2005) listed you to definitely sky levels of step 1,4-DCB had been very consistent within subjects off time to time; this might give an explanation for instance strong relationship ranging from blood and you may air levels of 1,4-DCB both in Sexton’s study and you may our very own comes from new NHANES studies (Desk 5).
Recommendations
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Variety of visibility users may also apply to dating ranging from VOC profile inside the bloodstream and you can heavens because ruled because of the operative toxicokinetic procedure
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